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Home Antibody All anti-NLRC3 antibodies

Anti-NLRC3 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320135 Rabbit Polyclonal NOD3 Antibody 100ug $325 3-7 Days
LC405859 NLRC3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenNOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
BufferNOD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NOD3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, CARD domain containing 3 (NLRC3), transcript variant 1
Alternative NameCLR16.2; NOD3
Database LinkNP_849172
Entrez Gene 197358 Human
Entrez Gene 268857 Mouse
Entrez Gene 287070 Rat
FunctionNOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NOD3 in 3T3 cell lysate with NOD3 antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunofluorescence of NOD3 in Jurkat cells with NOD3 antibody at 20 ug/mL.


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