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Home Antibody All anti-PRICKLE2 antibodies

Anti-PRICKLE2 Antibody Polyclonal


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SKU Description Amount Price Availability*  
TA320126 Rabbit Polyclonal PRICKLE2 Antibody 100ug $325 2 Weeks
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OriGene Data

ImmunogenPRICKLE2 antibody was raised against a 15 amino acid synthetic peptide near the center of human PRICKLE2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/mL, IF: 20 ug/mL
BufferPRICKLE2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification PRICKLE2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameprickle planar cell polarity protein 2
Alternative NameEPM5
Database LinkNP_942559
Entrez Gene 166336 Human
Entrez Gene 243548 Mouse
Entrez Gene 312563 Rat
FunctionPRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
Related Pathway Wnt signaling pathway

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WB Image
Western blot analysis of PRICKLE2 in A-20 lysate with PRICKLE2 antibody at 1 ug/mL.

IF Image
Immunofluorescence of PRICKLE2 in rat brain cells with PRICKLE2 antibody at 20 ug/mL.


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