Home Antibody All anti-TTYH2 antibodies
Anti-TTYH2 Antibody Polyclonal
Also for TTYH2 (NM_032646)
|TTYH2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human TTYH2.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 2.5 ug/ml
|TTYH2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TTYH2 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens tweety family member 2 (TTYH2), transcript variant 1|
|TTYH2 Antibody: TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels.|
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Western blot analysis of TTYH2 in human kidney tissue lysate with TTYH2 antibody at 1 ug/ml
Immunohistochemistry of TTYH2 in human kidney tissue with TTYH2 antibody at 2.5 ug/mL.