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Home Antibody All anti-CRACR2A antibodies

Anti-CRACR2A Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320057 Rabbit Polyclonal EFCAB4B Antibody 100ug $325 3-7 Days
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Also for CRACR2A (NM_032680)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenEFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferEFCAB4B Antibody is supplied in PBS containing 0.02% sodium azide.
Purification EFCAB4B Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens calcium release activated channel regulator 2A (CRACR2A), transcript variant 3
Alternative NameEFCAB4B; EFCAB4B
Database LinkNP_116069
Entrez Gene 84766 Human
Entrez Gene 381812 Mouse
FunctionEFCAB4B Antibody: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of EFCAB4B in mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 ug/mL.

IF Image
Immunofluorescence of EFCAB4B in human kidney tissue with EFCAB4B antibody at 20 ug/mL.


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