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Anti-KHDC1 Antibody Polyclonal
Also for KHDC1 (NM_030568)
|KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|KHDC1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|KHDC1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens KH homology domain containing 1 (KHDC1), transcript variant 2|
|bA257K9.4; C6orf148; NDG1|
|KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).|
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Western blot analysis of KHDC1 in rat liver tissue lysate with KHDC1 antibody at (A) 0.5 and (B) 1 ug/mL.