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Home Antibody All anti-FOXRED2 antibodies

Anti-FOXRED2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320025
  • Rabbit Polyclonal FOXRED2 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for FOXRED2 (NM_001102371)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFOXRED2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FOXRED2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, IF: 20 ug/ml
BufferFOXRED2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXRED2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens FAD-dependent oxidoreductase domain containing 2 (FOXRED2), transcript variant 2
Alternative NameERFAD
Database LinkNP_001095841
FunctionFOXRED2 Antibody: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FOXRED2 in human lung tissue lysate with FOXRED2 antibody at 1 ug/mL.
IF Image
Immunofluorescence of FOXRED2 in human lung cells with FOXRED2 antibody at 20 ug/mL.

 

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