Home Antibody All anti-ESRP2 antibodies
Anti-ESRP2 Antibody Polyclonal
Also for ESRP2 (NM_024939)
|RBM35B antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human RBM35B.|
||ELISA, WB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|RBM35B Antibody is supplied in PBS containing 0.02% sodium azide.|
|RBM35B Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens epithelial splicing regulatory protein 2 (ESRP2)|
|RBM35B Antibody: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.|
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Western blot analysis of RBM35B in human lung tissue lysate with RBM35B antibody at 1 ug/mL.
Immunohistochemistry of RBM35B in human lung tissue with RBM35B antibody at 5 ug/mL.