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Home Antibody All anti-DDA1 antibodies

Anti-DDA1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320007 Rabbit Polyclonal DDA Antibody 100ug $325 3-7 Days
LC411390 DDA1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenDDA1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DDA1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferDDA Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DDA Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens DET1 and DDB1 associated 1 (DDA1)
Alternative NameC19orf58; PCIA1
Database LinkNP_076955
Entrez Gene 79016 Human
Entrez Gene 66498 Mouse
Entrez Gene 688813 Rat
FunctionDDA Antibody: DDA1 (DET1 and DDB1 associated 1), along with DET1 and DDB1 and a member of the UBE2E group of canonical ubiquitin-conjugating enzymes, comprise DDD-E2 complexes, which interact with multiple ubiquitin E3 ligases. One of these E3 ligases is Cul4-containing E3 ligase complex CRL4. Cells depleted of DDA1 spontaneously accumulate double-stranded DNA breaks in a similar fashion as Cul4A-, Cul4B-, or WDR23-depleted cells, suggesting that DDA1 interacts with the CRL4 complex and may be involved in the ubiquitination and subsequent proteasomal degradation of target proteins.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DDA1 in mouse heart tissue lysate with DDA1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide

IHC Image
Immunohistochemistry of DDA1 in mouse heart tissue with DDA1 antibody at 5 ug/mL.

IF Image
Immunofluorescence of DDA1 in mouse heart tissue with DDA1 antibody at 20 ug/mL.


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