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Home Antibody All anti-DDA1 antibodies

Anti-DDA1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320007
  • Rabbit Polyclonal DDA Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411390) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for DDA1 (NM_024050)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDDA1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DDA1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferDDA Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DDA Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens DET1 and DDB1 associated 1 (DDA1)
Alternative NameC19orf58; PCIA1
Database LinkNP_076955
Entrez Gene 79016 Human
Entrez Gene 66498 Mouse
Entrez Gene 688813 Rat
FunctionDDA Antibody: DDA1 (DET1 and DDB1 associated 1), along with DET1 and DDB1 and a member of the UBE2E group of canonical ubiquitin-conjugating enzymes, comprise DDD-E2 complexes, which interact with multiple ubiquitin E3 ligases. One of these E3 ligases is Cul4-containing E3 ligase complex CRL4. Cells depleted of DDA1 spontaneously accumulate double-stranded DNA breaks in a similar fashion as Cul4A-, Cul4B-, or WDR23-depleted cells, suggesting that DDA1 interacts with the CRL4 complex and may be involved in the ubiquitination and subsequent proteasomal degradation of target proteins.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DDA1 in mouse heart tissue lysate with DDA1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide
IHC Image
Immunohistochemistry of DDA1 in mouse heart tissue with DDA1 antibody at 5 ug/mL.
IF Image
Immunofluorescence of DDA1 in mouse heart tissue with DDA1 antibody at 20 ug/mL.

 

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