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Home Antibody All anti-ATG3 antibodies

Anti-ATG3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320002
  • Rabbit Polyclonal ATG3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411559) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for ATG3 (NM_022488)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenATG3 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferATG3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ATG3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens autophagy related 3 (ATG3), transcript variant 1
Alternative NameAPG3; APG3-LIKE; APG3L; PC3-96
Database LinkNP_071933
FunctionATG3 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. It functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.
Related Pathway

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WB Image
Western blot analysis of ATG3 in Mouse kidney tissue Lysate with ATG3 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of ATG3 in human kidney with ATG3 antibody at 20 ug/mL.

 

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