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Home Antibody All anti-TYW1 antibodies

Anti-TYW1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319957
  • Rabbit Polyclonal TYW1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413176) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenTYW1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TYW1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 ug/ml, IHC: 5 ug/ml
BufferTYW1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TYW1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) (TYW1)
Alternative NameRSAFD1; TYW1A; YPL207W
Database LinkNP_060734
FunctionTYW1 Antibody: TYW1, also known as TYW1A, RSAFD1 or YPL207W, is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7. Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome, suggesting that TYW1 may play a role in these conditions
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TYW1 in human lung tissue lysate with TYW1 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of TYW1 in human lung tissue with TYW1 antibody at 5 ug/mL.

 

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