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Home Antibody All anti-BANP antibodies

Anti-BANP Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319948
  • Rabbit Polyclonal BANP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC433197) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for BANP (NM_001173539)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenBANP antibody was raised against a 14 amino acid synthetic peptide near the center of human BANP.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
BufferBANP Antibody is supplied in PBS containing 0.02% sodium azide.
Purification BANP Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens BTG3 associated nuclear protein (BANP), transcript variant 3
Alternative NameBEND1; SMAR1; SMARBP1
Database LinkNP_001167010
FunctionBANP Antibody: BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen. BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest. p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop. BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling. Furthermore, BANP can modulate NF-κB transactivation and can inhibit tumorigenesis by regulating NF-κB target genes. Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of BANP in mouse kidney tissue lysate with BANP antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of BANP in human kidney tissue with BANP antibody at 10 ug/mL.
IF Image
Immunofluorescence of BANP in human kidney tissue with BANP antibody at 20 ug/mL.

 

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