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Home Antibody All anti-FAM193B antibodies

Anti-FAM193B Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319939
  • Rabbit Polyclonal FAM193B Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenFAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, IF: 20 ug/ml
BufferFAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FAM193B Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens family with sequence similarity 193, member B (FAM193B), transcript variant 1
Alternative NameDKFZp313I142; FLJ10404; KIAA1931
Database LinkNP_061930
Entrez Gene 54540 Human
FunctionFAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 ug/mL.

 

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