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Home Antibody All anti-TRIM33 antibodies

Anti-TRIM33 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319933 Rabbit Polyclonal TRIM33 Antibody 100ug $325 3-7 Days
LC414337 TRIM33 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenTRIM33 antibody was raised against an 18 amino acid peptide near the center of human TRIM33.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation Predicted: 70, 124 kDa Observed: 70 kDa
BufferTRIM33 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TRIM33 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nametripartite motif containing 33
Database LinkNP_056990
Entrez Gene 51592 Human
Entrez Gene 94093 Mouse
Entrez Gene 365894 Rat
FunctionTRIM33 Antibody: TRIM24 (TIF1alpha), TRIM28 (TIF1beta), and TRIM33 (TIF1gamma) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors (1-2). The structure of TRIM33 is similar to TRIM24 and TRIM28, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain) (3). TRIM33 functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells (3). It interacts with the Smad2/3 transcription factor in hematopoietic, mesenchymal, and epithelial cell types to mediate different transcriptional effects in response to TGF-beta (4). It acts as an E3 ubiquitin-protein ligase and promotes SMAD4 ubiquitination (5).
Related PathwayProtein KinaseES Cell Differentiation/IPSTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TRIM33 in human liver tissue lysate with TRIM33 antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of TRIM33 in human liver tissue with TRIM33 antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of TRIM33 in human liver tissue with TRIM33 antibody at 20 ug/mL.


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