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Anti-TLR8 Antibody Polyclonal
Also for TLR8 (NM_138636)
|TLR8 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TLR8.|
||ELISA, IHC: 5 ug/ml
|TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TLR8 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens toll-like receptor 8 (TLR8), transcript variant 2|
Entrez Gene 51311 Human
|TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.|
|TransmembraneDruggable Genome Toll-like receptor signaling pathway|
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Immunohistochemistry of TLR8 in human thymus tissue with TLR8 antibody at 5 ug/mL.