Home Antibody All anti-LRRTM2 antibodies
Anti-LRRTM2 Antibody Polyclonal
Also for LRRTM2 (NM_015564)
|LRRTM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM2.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|LRRTM2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|LRRTM2 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens leucine rich repeat transmembrane neuronal 2 (LRRTM2)|
|LRRTM2 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.|
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Western blot analysis of LRRTM2 in SK-N-SH cell lysate with LRRTM2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of LRRTM2 in human brain tissue with LRRTM2 antibody at 2.5 ug/mL.