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Home Antibody All anti-ZNF521 antibodies

Anti-ZNF521 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319875
  • Rabbit Polyclonal ZNF521 Antibody
100ug $325 3-7 Days
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IHC(1)
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Also for ZNF521 (NM_015461)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenZNF521 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ZNF521.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *IHC Suggested DilutionsELISA, IHC: 5 ug/ml
BufferZNF521 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ZNF521 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens zinc finger protein 521 (ZNF521)
Alternative NameEHZF; Evi3
Database LinkNP_056276
FunctionZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Related Pathway

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IHC Image
Immunohistochemistry of ZNF521 in human kidney tissue with ZNF521 antibody at 5 ug/mL.

 

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