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Home Antibody All anti-TMEM59L antibodies

Anti-TMEM59L Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319872 Rabbit Polyclonal TMEM59L Antibody 100ug $325 In Stock
LC415978 TMEM59L HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenTMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferTMEM59L Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TMEM59L Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens transmembrane protein 59 like (TMEM59L)
Alternative NameBSMAP; C19orf4
Database LinkNP_036241
Entrez Gene 25789 Human
Entrez Gene 67937 Mouse
Entrez Gene 306349 Rat
FunctionTMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of TMEM59L in mouse brain tissue with TMEM59L antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of TMEM59L in mouse brain tissue with TMEM59L antibody at 20 ug/mL.


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