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Home Antibody All anti-RASD2 antibodies

Anti-RASD2 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319863 Rabbit Polyclonal TEM2 Antibody 100ug $325 3-7 Days
LC415366 RASD2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for RASD2 (NM_014310)
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OriGene Data

ImmunogenTEM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferTEM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TEM2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens RASD family, member 2 (RASD2)
Alternative NameMGC:4834; Rhes; TEM2
Database LinkNP_055125
Entrez Gene 23551 Human
Entrez Gene 75141 Mouse
Entrez Gene 171099 Rat
FunctionTEM2 Antibody: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TEM2 in human colon tissue lysate with TEM2 antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of TEM2 in human colon tissue with TEM2 antibody at 2.5 ug/mL.
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