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Home Antibody All anti-ZEB2 antibodies

Anti-ZEB2 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319793 Rabbit Polyclonal ZEB2 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenZEB2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ZEB2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
BufferZEB2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ZEB2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 2
Alternative NameHSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
Database LinkNP_001165124
Entrez Gene 9839 Human
Entrez Gene 24136 Mouse
Entrez Gene 311071 Rat
FunctionZEB2 Antibody: ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ZEB2 in Jurkat cell lysate with ZEB2 antibody at (A) 1 and (B) 2ug/mL.

IF Image
Immunocytochemistry of ZEB2 in Jurkat cells with ZEB2 antibody at 20 ug/mL.

IF Image
Immunofluorescence of ZEB2 in Jurkat cells with ZEB2 antibody at 20 ug/mL.


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