OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PIAS1 antibodies

Anti-PIAS1 Antibody Polyclonal

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319754
  • Rabbit Polyclonal PIAS1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402513) , 20ug
100ug 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenPIAS1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PIAS1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPIAS1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification PIAS1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens protein inhibitor of activated STAT, 1 (PIAS1)
Alternative NameDDXBP1; GBP; GU/RH-II; ZMIZ3
Database LinkNP_057250
FunctionPIAS1 Antibody: The PIAS proteins (protein inhibitor of activated STAT) play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS1. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS1 binds specifically to STAT1, inhibiting STAT1-mediated gene activation and also binds to the Gu/RNA helicase II enzyme, leading to the proteolytic cleavage of Gu/RH-II. PIAS1 is a potent co-activator for CP2c-mediated alpha-globin expression in erythroid cells.
Related Pathway
Jak-STAT signaling pathway
TGF Beta Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PIAS1 in human kidney tissue lysate with PIAS1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of PIAS1 in rat kidney tissue with PIAS1 antibody at 5 ug/mL.
IF Image
Immunofluorescence of PIAS1 in rat kidney tissue with PIAS1 antibody at 20 ug/mL.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title