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Home Antibody All anti-AXIN1 antibodies

Anti-AXIN1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319744
  • Rabbit Polyclonal AXIN1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418638) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenAXIN1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferAXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification AXIN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens axin 1 (AXIN1), transcript variant 1
Alternative NameAXIN; PPP1R49
Database LinkNP_003493
FunctionAXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot analysis of AXIN1 in SK-N-SH cell lysate with AXIN1 antibody at 1 ug/mL.
IF Image
Immunofluorescence of AXIN1 in human brain tissue with AXIN1 antibody at 20 ug/mL.

 

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