Home Antibody All anti-UPK1B antibodies
Anti-UPK1B Antibody Polyclonal
Also for UPK1B (NM_006952)
|UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|UPK1B Antibody is supplied in PBS containing 0.02% sodium azide.|
|UPK1B Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens uroplakin 1B (UPK1B)|
|TSPAN20; UPIB; UPK1|
|UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.|
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Western blot analysis of UPK1B in mouse bladder tissue lysate with UPK1B antibody at (A) 0.5 and (B) 1 ug/mL.
Immunohistochemistry of UPK1B in human bladder tissue with UPK1B antibody at 5 ug/mL.