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Home Antibody All anti-TYK2 antibodies

Anti-TYK2 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319732 Rabbit Polyclonal TYK2 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenRabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation 131 kDa
BufferTYK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TYK2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens tyrosine kinase 2 (TYK2)
Alternative NameIMD35; JTK1
Database LinkNP_003322
Entrez Gene 7297 Human
Entrez Gene 54721 Mouse
Entrez Gene 100361294 Rat
FunctionTYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Related PathwayProtein KinaseDruggable Genome Jak-STAT signaling pathway

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WB Image
Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 ug/mL


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