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Anti-TYK2 Antibody Polyclonal
Also for TYK2 (NM_003331)
|Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|TYK2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TYK2 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens tyrosine kinase 2 (TYK2)|
|TYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.|
Jak-STAT signaling pathway
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Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 ug/mL