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Anti-TLR4 Antibody Polyclonal
Also for TLR4 (NM_003266)
|TLR4 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TLR4.|
||ELISA, IHC: 5 ug/ml
|TLR4 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TLR4 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens toll-like receptor 4 (TLR4), transcript variant 3|
|ARMD10; CD284; TLR-4; TOLL|
Entrez Gene 7099 Human
|TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.|
|TransmembraneDruggable Genome Toll-like receptor signaling pathwayPathogenic Escherichia coli infection|
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Immunohistochemistry of TLR4 in human placenta tissue with TLR4 antibody at 5 ug/mL.