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Home Antibody All anti-CCL4 antibodies

Anti-CCL4 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319702 Rabbit Polyclonal CCL4 Antibody 100ug $325 3-7 Days
LC401043 CCL4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation 10 kDa
BufferCCL4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification CCL4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameC-C motif chemokine ligand 4
Alternative NameACT2|AT744.1|G-26|HC21|LAG-1|LAG1|MIP-1-beta|MIP1B|MIP1B1|SCYA2|SCYA4
Database LinkNP_002975
Entrez Gene 6351 Human
Entrez Gene 20303 Mouse
Entrez Gene 116637 Rat
FunctionCCL4 Antibody: CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ; with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayToll-like receptor signaling pathwayCytosolic DNA-sensing pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CCL4 in rat brain tissue lysate with CCL4 antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of CCL4 in rat brain tissue with CCL4 antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of CCL4 in rat brain tissue with CCL4 antibody at 20 ug/mL.


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