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Home Antibody All anti-CCL4 antibodies

Anti-CCL4 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319702
  • Rabbit Polyclonal CCL4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401043) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for CCL4 (NM_002984)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC, IF
BufferCCL4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification CCL4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) ligand 4 (CCL4)
Alternative NameACT2; AT744.1; G-26; HC21; LAG-1; LAG1; MIP-1-beta; MIP1B; MIP1B1; SCYA2; SCYA4
Database LinkNP_002975
FunctionCCL4 Antibody: CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ; with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.
Related Pathway
Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CCL4 in rat brain tissue lysate with CCL4 antibody at 1 ug/mL.

 

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