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Home Antibody All anti-RAF1 antibodies

Anti-RAF1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319697 Chicken Polyclonal C-raf Antibody 100ug $325 3-7 Days
LC419048 RAF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenC-raf antibody was raised against an 19 amino acid synthetic peptide near the amino terminus of human C-raf.
Clone NamePolyclonal IsotypeIgY
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
BufferC-raf Antibody is supplied in PBS containing 0.02% sodium azide.
Purification C-raf Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens Raf-1 proto-oncogene, serine/threonine kinase (RAF1)
Alternative Namec-Raf; CMD1NN; CRAF; NS5; Raf-1
Database LinkNP_002871
Entrez Gene 5894 Human
Entrez Gene 110157 Mouse
Entrez Gene 24703 Rat
FunctionC-raf Antibody: C-raf is the cellular homolog of viral raf gene (v-raf) and encodes a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases. Once activated, C-raf phosphorylates and activates the protein kinases MEK1 and MEK2, which in turn phosphorylate and activate the serine/threonine specific protein kinases, ERK1 and ERK2. These activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayVascular smooth muscle contractionVEGF signaling pathwayFocal adhesionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of C-raf in 3T3 cell lysate with C-raf antibody at (A) 0.5 and (B) 1 ug/mL.


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