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Home Antibody All anti-TM4SF1 antibodies

Anti-TM4SF1 Antibody Polyclonal


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SKU Description Amount Price Availability*  
TA319680 Rabbit Polyclonal TM4SF1 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenTM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferTM4SF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TM4SF1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nametransmembrane 4 L six family member 1
Alternative NameH-L6|L6|M3S1|TAAL6
Database LinkNP_055035
Entrez Gene 4071 Human
Entrez Gene 17112 Mouse
Entrez Gene 295061 Rat
FunctionTM4SF1 Antibody: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TM4SF1 in human lung tissue lysate with TM4SF1 antibody at (A) 0.5 and (B) 1 ug/mL.

IHC Image
Immunohistochemistry of TM4SF1 in human lung tissue with TM4SF1 antibody at 5 ug/mL.

IF Image
Immunofluorescence of TM4SF1 in human lung tissue with TM4SF1 antibody at 20 ug/mL.


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