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Home Antibody All anti-LIF antibodies

Anti-LIF Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319675
  • Rabbit Polyclonal LIF Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400835) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for LIF (NM_002309)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLIF antibody was raised against a 16 amino acid synthetic peptide near the center of human LIF.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferLIF Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LIF Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leukemia inhibitory factor (LIF), transcript variant 1
Alternative NameCDF; DIA; HILDA; MLPLI
Database LinkNP_002300
FunctionLIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.
Related Pathway
Adipogenesis
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
TGF Beta Signaling Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LIF in 3T3 cell lysate with LIF antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of LIF in 3T3 cells with LIF antibody at 20 ug/mL.

 

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