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Home Antibody All anti-KPNA3 antibodies

Anti-KPNA3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319673
  • Rabbit Polyclonal KPNA3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400821) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for KPNA3 (NM_002267)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenKPNA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy end of human KPNA3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferKPNA3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KPNA3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens karyopherin alpha 3 (importin alpha 4) (KPNA3)
Alternative NamehSRP1; IPOA4; SRP1; SRP1gamma; SRP4
Database LinkNP_002258
FunctionKPNA3 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.
Related Pathway

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WB Image
Western blot analysis of KPNA3 in EL4 cell lysate with KPNA3 antibody at (A) 1 and (B) 2 µg/mL.
IHC Image
Immunocytochemistry of KPNA3 in HeLa cells with KPNA3 antibody at 10 µg/mL.
IF Image
Immunofluorescence of KPNA3 in EL4 cells with KPNA3 antibody at 20 µg/mL.

 

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