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Home Antibody All anti-IRF4 antibodies

Anti-IRF4 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319669
  • Rabbit Polyclonal IRF4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419304) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenIRF4 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human IRF4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferIRF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IRF4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens interferon regulatory factor 4 (IRF4), transcript variant 2
Alternative NameLSIRF; MUM1; NF-EM5
Database LinkNP_001182215
FunctionIRF4 Antibody: Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.
Related Pathway
Apoptosis

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IRF4 in Jurkat cell lysate with IRF4 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunofluorescence of IRF4 in Jurkat cells with IRF4 antibody at 20 ug/mL.

 

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