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Home Antibody All anti-FOXO1 antibodies

Anti-FOXO1 Antibody Polyclonal

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319651 Rabbit Polyclonal FOXO1 Antibody 100ug $325 3-7 Days
LC419586 FOXO1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)
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Also for FOXO1 (NM_002015)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFOXO1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human FOXO1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/mL, ICC:4 ug/mL, IF: 20 ug/mL
BufferFOXO1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXO1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target Nameforkhead box O1
Alternative NameFKH1|FKHR|FOXO1A
Database LinkNP_002006
Entrez Gene 2308 Human
Entrez Gene 56458 Mouse
Entrez Gene 84482 Rat
FunctionFOXO1 Antibody: FOXO1, also known as FKHR or ForkHead in Rhabdomyosarcoma, is a 70 kDa protein which is a ubiquitously expressed member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In insulin-responsive tissues, stress or nutrient abundance triggers phosphorylation by PKB/AKT, blocking nuclear translocation and activity. Genetic mutations involving FOXO1A are a cause of alveolar rhabdomyosarcoma (RMS2). Recent studies link the anti-tumor activity of FOXO1 and the process of autophagy.
Related PathwayTranscription FactorsDruggable Genome Insulin signaling pathwayPathways in cancerProstate cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of FOXO1 in Hela cell lysate with FOXO1 antibody at 1 ug/mL.
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IF Image
Immunocytochemistry of FOXO1 in HeLa cells with FOXO1 antibody at 4 ug/mL.
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