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Anti-ESR1 Antibody Polyclonal
Also for ESR1 (NM_000125)
|ESR1 antibody was raised against an 18 amino acid peptide near the center of human ESR1.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|ESR1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|ESR1 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1|
|ER; Era; ESR; ESRA; ESTRR; NR3A1|
|ESR1 Antibody: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1). Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3).|
TGF Beta Signaling Pathway
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Western blot analysis of ESR1 in rat brain tissue lysate with ESR1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.