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Anti-BOK Antibody Polyclonal
|BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK.|
||ELISA, IHC: 5 ug/ml
|BOK Antibody is supplied in PBS containing 0.02% sodium azide.|
|BOK Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens BCL2-related ovarian killer (BOK)|
|BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.|
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Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 ug/mL.