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Home Antibody All anti-APBA1 antibodies

Anti-APBA1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319613 Rabbit Polyclonal APBA1 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenAPBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 ug/mL, IF: 20 ug/mL
Predicted MW Explanation 92 kDa
BufferAPBA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APBA1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens amyloid beta precursor protein binding family A member 1 (APBA1)
Alternative NameD9S411E; LIN10; MINT1; X11; X11A; X11ALPHA
Database LinkNP_001154
Entrez Gene 320 Human
Entrez Gene 319924 Mouse
Entrez Gene 83589 Rat
FunctionAPBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.

IF Image
Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 ug/mL.


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