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Anti-AFP Antibody Polyclonal
|AFP antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human AFP.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|AFP Antibody is supplied in PBS containing 0.02% sodium azide.|
|AFP Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens alpha-fetoprotein (AFP)|
|AFP Antibody: Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma. However, hereditary persistance of AFP may also be found in individuals with no obvious pathology. AFP is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. AFP levels in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.|
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Western blot analysis of AFP in human liver tissue lysate with AFP antibody at 1 ug/mL.
Immunohistochemistry of AFP in rat liver tissue with AFP antibody at 10 ug/mL.