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Home Antibody All anti-IL17F antibodies

Anti-IL17F Antibody 4H1629.1

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SKU Description Amount Price Availability*  
TA319598 Mouse monoclonal Anti-Human IL-17F Biotin Conjugated antibody 100ug $325 In Stock
LC403264 IL17F HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for IL17F (NM_052872)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenAnti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Clone Name4H1629.1 Isotype
Species Reactivityhuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 mg/mL, IHC: 5ug/mL
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.

Reference Data

Target NameHomo sapiens interleukin 17F (IL17F)
Alternative NameCANDF6; IL-17F; ML-1; ML1
Database LinkNP_443104
Entrez Gene 112744 Human
Function
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western Blot of Mouse Anti-IL-17F antibody Lane 1: human full length recombinant IL-17F protein Lane 2: mouse full length recombinant IL-17F protein Lane 3: rat full length recombinant IL-17F protein Load: 20 ng/lane Primary antibody: Anti-IL-17F antibody at 0.5ug/mL for overnight at 4°C
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Immunohistochemistry of Mouse Anti-IL-17F antibody Tissue: human colon tissue Fixation: formalin-fixed, paraffin-embedded Primary antibody: isotype control (top left) , Mouse Anti-IL-17F antibody (bottom left, right) at 5 ug/mL
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