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Home Antibody All anti-HUS1B antibodies

Anti-HUS1B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319520
  • Rabbit polyclonal anti-Hus1B antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC407722) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 104-117 of human Hus1B protein.
Clone Name IsotypeIgG
Species Reactivityhuman, mouse, rat Concentration1.75 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:20,000 - 1:100,000, WB: 1:500 - 1:5,000, IP: 1:100
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note The protein encoded by the Hus1B gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the checkpoint protein RAD1 but not with RAD9. Over expression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to HUS1. Hus1B is expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.

Reference Data

Target NameHomo sapiens HUS1 checkpoint homolog b (S. pombe) (HUS1B)
Alternative NameRP11-532F6.1
Database LinkNP_683762
Entrez Gene 135458 Human
Entrez Gene 210554 Mouse
Entrez Gene 691382 Rat
Function
Related Pathway

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WB Image
Western blot using affinity purified anti-Hus1B antibody shows detection of a 36kDa band corresponding to Hus1B in a HeLa cell lysate (arrowhead). The staining pattern in 293 cells is less clear, showing a predominant band at 39 kDa. Personal Communication, A-Lien Lu-Chang, U. Maryland, Baltimore, MD

 

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