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Home Antibody All anti-HIST1H3A antibodies

Anti-HIST1H3A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319430 Rabbit polyclonal Histone H3 antibody 100ul $325 3-7 Days
LC418617 HIST1H3A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenAnti-Histone-3 was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to the c-terminus region of human histone-3.
Clone Name IsotypeIgG
Species Reactivityhuman Concentration83 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:10000, WB: 1:2000
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Histone proteins are highly post-translationally modified with Histone H3 being the most extensively modified of the five histones. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone H3 Antibody is ideal for investigators involved in Cell Signaling, Epigenetics, Nuclear Signaling research and Signal Transduction research.

Reference Data

Target NameHomo sapiens histone cluster 1, H3a (HIST1H3A)
Alternative NameH3/A; H3FA
Database LinkNP_003520
Entrez Gene 8350 Human
Related Pathway Systemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot of Rabbit anti-Histone 3 antibody. Lane 1: Raji lysate. Lane 2: HeLa lysate. Load: 15ug, 25ug respectively. Primary antibody: Histone 3 antibody at 1:2000 for overnight at 4°C. Secondary antibody: IRDye800™ rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 15.4 kDa, ~15.4 kDa for Histone 3. Other band(s): none.


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