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Home Antibody All anti-IL4 antibodies

Anti-IL4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319287
  • Rabbit polyclonal IL-4 antibody Peroxidase Conjugated
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424622) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for IL4 (NM_000589)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-4 protein.
Clone Name IsotypeIgG
Species Reactivityhuman Concentration1.0 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:10,000-1:50,000, WB: 1:1,000-1:5,000, IHC: 1:500;1:2,500
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note IL-4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Reference Data

Target NameHomo sapiens interleukin 4 (IL4), transcript variant 1
Alternative NameBCGF-1; BCGF1; BSF-1; BSF1; IL-4
Database LinkNP_000580
Entrez Gene 3565 Human
Function
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayHematopoietic cell lineageT cell receptor signaling pathwayFc epsilon RI signaling pathwayAsthmaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot of Rabbit Anti - IL-4 Antibody Peroxidase Conjugated Lane 1: Human IL-4 Load: 50 ng per lane Secondary antibody: IL-4 Antibody Peroxidase Conjugated at 1:1,000 for 60 min at RT Block: MB-070 for 30 min RT Predicted/Observed size: 18 kDa, 18 kDa

 

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