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Home Antibody All anti-PTGS2 antibodies

Anti-PTGS2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319280 Rabbit polyclonal anti-Cox-2 antibody 100ul $356 3-7 Days
LC424429 PTGS2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenThis whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
Clone Name IsotypeIgG
Species Reactivityhuman, mouse, rat Concentration55 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:10,000 - 1:50,000, WB: 1:5,000 - 1:10,000, IHC: User Optimized
Note COX-2, also known as prostaglandin H synthase, was identified less than a decade ago.  Its discovery was followed by a period of discovery and drug development to create a “super aspirin” and led to insights into arthritis, Alzheimer's disease, colorectal cancer and regulation of brain and kidney function in search of better treatments for degenerative and inflammatory diseases.   Two different isoforms of the enzyme are known, Cox-1 and  Cox and Cox-2.

Reference Data

Target NameHomo sapiens prostaglandin-endoperoxide synthase 2 (PTGS2)
Alternative NameCOX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2
Database LinkNP_000954
Entrez Gene 5743 Human
Entrez Gene 19225 Mouse
Entrez Gene 29527 Rat
Related PathwayDruggable Genome Arachidonic acid metabolismVEGF signaling pathwayPathways in cancerSmall cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
anti-Cox2 is shown to detect Cox-2 present in Cox-2 transfected Sf9 cell extract (lane 1) and IL-1ß induced WISH cell extract (lane 2). Detection occurs using a 1:10,000 dilution of antibody followed by 1:10,000 dilution of HRP Goat-a-Rabbit with visualization via ECL. Film exposure approximately 1’. Other detection systems will yield similar results.


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