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Home Antibody All anti-UBE2J1 antibodies

Anti-UBE2J1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319235 Rabbit polyclonal anti-UBE2J1 antibody 100ug $325 3-7 Days
LC414230 UBE2J1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for UBE2J1 (NM_016021)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues near the amino terminus of the human Ube2j1 protein.
Clone Name IsotypeIgG
Species Reactivityhuman Concentration0.71 mg/mL
Guaranteed Application *WB Suggested DilutionsELISA: 1:1,000 - 1:5,000, WB: 1:200 - 1:2,000, IP: 1-2 ug
Buffer0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Note This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Ube2j1 and Ube2j2 are homologs of the yeast ubiquitin-conjugating enzyme UBC6, which catalyzes the covalent attachment of ubiquitin to other proteins. These proteins constitute a distinct family of ubiquitin-conjugating enzymes sharing a conserved non-canonical active site sequence and a C-terminal transmembrane domain.  By analogy with yeast UBC6, Ube2j1 and Ube2j2 are localized to the endoplasmic reticulum and seem to function in the selective degradation of misfolded membrane proteins and in general mediation of the stress response.

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2, J1 (UBE2J1)
Alternative NameCGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p
Database LinkNP_057105
Entrez Gene 51465 Human
Function
Related PathwayTransmembrane Ubiquitin mediated proteolysisParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot using affinity purified anti-Ube2j1 antibody shows detection of Ube2j1 in 293 cells over-expressing Myc-Ube2j1 (Lane 2). Lane 1 contains lysate from mock-transfected 293 cells. Personal Communication, A. Weissman & T. Shang, CCR-NCI, Frederick, MD
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