Home Antibody All anti-WDR5 antibodies
Also for WDR5 (NM_052821)
|WDR5 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human WDR5.|
|WB, IHC, IF
||WB: 1ug/ml, ICC: 5ug/ml, ELISA
|100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.|
|Affinity chromatography purified via peptide column
|Homo sapiens WD repeat domain 5 (WDR5), transcript variant 2|
|BIG-3; CFAP89; SWD3|
Entrez Gene 11091 Human
|WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.|
|Druggable Genome |
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Western blot analysis of WDR5 in 293 cell lysate with WDR5 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of WDR5 in 293 cells with WDR5 antibody at 5 µg/mL.
Immunocytochemistry of 293 cells with WDR5 antibody at 5ug/ml.