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Home Antibody All anti-TGFB2 antibodies

Anti-TGFB2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319077
  • Rabbit polyclonal anti-TGF-beta2 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401115) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for TGFB2 (NM_003238)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenE. coli expressed recombinant human TGF-ß2
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens transforming growth factor, beta 2 (TGFB2), transcript variant 2
Alternative NameLDS4; TGF-beta2
Database LinkNP_003229
Entrez Gene 7042 Human
Entrez Gene 21808 Mouse
Entrez Gene 81809 Rat
FunctionThe three mammalian isoforms of TGF-beta (TGF-beta1, TGF-beta2, TGF-beta3) signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development.
Related PathwaySecreted ProteinTransmembraneDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionCell cycleTGF-beta signaling pathwayPathways in cancerColorectal cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using recombinant human TGF-beta2. Lane 1: 5 ng, Lane 2: 10 ng, Lane 3: 50 ng, Lane 4: 100 ng.

 

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