Home Antibody All anti-PANX1 antibodies
Also for PANX1 (NM_015368)
|Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.|
|Human, Mouse, Rat
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens pannexin 1 (PANX1)|
|MRS1; PX1; UNQ2529|
Entrez Gene 24145 Human
Entrez Gene 55991 Mouse
Entrez Gene 315435 Rat
|The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1 µg/mL.