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Home Antibody All anti-PTK6 antibodies

Anti-PTK6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318981
  • Rabbit polyclonal anti-PTK6 (Brk) antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416957) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for PTK6 (NM_005975)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to residues surrounding amino acids 508 of human Brk
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens protein tyrosine kinase 6 (PTK6), transcript variant 1
Alternative NameBRK
Database LinkNP_005966
FunctionBreast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion

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WB Image
Western blot analysis of Brk in lysates from Jurkat cells (Lane 1,2), 3T3 cells (Lane 3) and rat kidney (Lane 4).

 

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