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Home Antibody All anti-Mmp11 antibodies

Anti-Mmp11 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318918
  • Rabbit polyclonal anti-MMP-11 antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 464 of mouse MMP-11
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens matrix metallopeptidase 11 (stromelysin 3) (MMP11)
Alternative NameSL-3; ST3; STMY3
Database LinkNP_005931
Entrez Gene 4320 Human
Entrez Gene 17385 Mouse
Entrez Gene 25481 Rat
FunctionThe matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
Related PathwayProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MMP-11 in Jurkat cell lysate (Lane 1& 2).

 

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