Home Antibody All anti-Mmp11 antibodies
Also for Mmp11 (NM_005940)
|Synthetic peptide surrounding amino acid 464 of mouse MMP-11 |
|Human, mouse, rat
|100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens matrix metallopeptidase 11 (stromelysin 3) (MMP11)|
|SL-3; ST3; STMY3|
Entrez Gene 4320 Human
Entrez Gene 17385 Mouse
Entrez Gene 25481 Rat
|The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.|
|ProteaseDruggable Genome |
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Western blot analysis of MMP-11 in Jurkat cell lysate (Lane 1& 2).