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Anti-Prf1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318899
  • Rabbit polyclonal anti-Perforin antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenRecombinant rat perforin
Clone Name IsotypeRabbit IgG
Species ReactivityMouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-Perforin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens perforin 1 (pore forming protein) (PRF1), transcript variant 1
Alternative NameFLH2; HPLH2; P1; PFN1; PFP
Database LinkNP_005032
FunctionPerforin (Pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte (CTL). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infection.
Related Pathway
Apoptosis

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WB Image
Western blot analysis of Perforin in rat kidney glomerulars.

 

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