Home Antibody All anti-Tctn2 antibodies
Also for Tctn2 (NM_001143850)
|Synthetic peptide surrounding amino acid 435 of rat TCTN2|
|Human, mouse, rat
|100 µg (0.5 mg/ml) affinity purified rabbit anti- TCTN2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Homo sapiens tectonic family member 2 (TCTN2), transcript variant 2|
|C12orf38; MKS8; TECT2|
Entrez Gene 79867 Human
Entrez Gene 67978 Mouse
Entrez Gene 689779 Rat
|TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog (Hh)-signaling pathway. Defects in TCTN2 can lead to Meckel syndrome type 8. This disorder is characterized by a combination of renal cysts and variable associated features which includes developmental anomalies of the central nervous system, hepatic ductal dysplasia and cysts, and polydactyly.|
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Western blot analysis of TCTN2 using Jurkat cell lysate (Lane 1) and 3T3 cell lysate (Lane 2).