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Anti-BTK PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA313378
  • Rabbit polyclonal BTK (Tyr551) antibody(Phospho-specific)
100ul $325 3 Weeks
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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human BTK around the phosphorylation site of tyrosine 551 (D-E-YP-T-S).
Clone Name IsotypeIgG
Species ReactivityHuman: Tyr551; Mouse: Tyr551; Rat:Tyr552 Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500~1:3000, ELISA: 1:40000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note BTK (phospho-Tyr551) antibody detects endogenous levels of BTK only when phosphorylated at tyrosine 551.

Reference Data

Target NameHomo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), transcript variant 1
Alternative NameAGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Database LinkNP_000052
Entrez Gene 695 Human
Entrez Gene 12229 Mouse
Entrez Gene 367901 Rat
Function
Related PathwayProtein KinaseDruggable Genome B cell receptor signaling pathwayFc epsilon RI signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts from HeLa cells, treated with H2O2 (100uM, 30mins), using BTK (phospho-Tyr551) antibody.The lane on the right is treated with the synthesized peptide.
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