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Home Antibody All anti-CASP3 antibodies

Anti-CASP3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA312442
  • Rabbit polyclonal Caspase 3 (Cleaved-Asp175) antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403215) , 20ug Explanation
100ul 325 3 Weeks
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WB(1)
IHC(1)
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Also for CASP3 (NM_032991)
cDNA Clone shRNA/siRNA Protein/Lysate Antibody Assay

OriGene Data

ImmunogenThe antiserum was produced against synthesized peptide derived from human Caspase 3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:20000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Caspase 3 (cleaved-Asp175) antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.

Reference Data

Target NameHomo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant beta
Alternative NameCPP32; CPP32B; SCA-1
Database LinkNP_116786
Entrez Gene 836 Human
Entrez Gene 12367 Mouse
Entrez Gene 25402 Rat
Function
Related PathwayES Cell Differentiation/IPSProteaseDruggable Genome MAPK signaling pathwayp53 signaling pathwayApoptosisNatural killer cell mediated cytotoxicityAlzheimer's diseaseParkinson's diseaseMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts from 293 cells, treated with Etoposide (25uM, 60mins), using Caspase 3 (cleaved-Asp175) antibody.The lane on the right is treated with the synthesized peptide.
IHC Image
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 3 (cleaved-Asp175) antibody.The picture on the right is treated with the synthesized peptide.

 

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